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As reported in other pneumococcal STM studies [10], [11], we did not identify any mutants that represent the capsule biosynthetic gene cluster.
We queried a previously described collection of ~450 yeast TS mutants that represent approximately 40% of the essential genes in the yeast genome (Li et al. 2011).
We constructed double mutants by mating a tel1 Δ query strain to an ordered array of ∼4800 nonessential gene deletion mutants that represent ∼80% of all yeast genes (Tong and Boone 2006).
Although Arabidopsis mutants that represent multiple mutation alleles of AtPP2 have been generated [ 27, 28], subsequent biological effects have not been studied, and especially, effects of AtPP2 mutations on the plant resistance to insects are unclear.
For example, the budding yeast cell cycle model has mutants that represent the organism when grown in different media.
Similar(55)
To understand the contribution of the individual D6PK genes to auxin transport in inflorescence stems, we measured basipetal auxin transport in primary inflorescence stems of a selected set of d6pk single, double and triple mutants that represented a previously established phenotypic series (Zourelidou et al., 2009; Willige et al., 2013).
A bni1 ∆ mutant that represents the Bni1p protein that acts downstream of Pkc1p independently of the CWI MAPK cascade to affect the actin cytoskeleton is defective for mat formation (Evangelista et al. 1997) but also has defects in invasive growth (data not shown).
We computed a lifespan score for each mutant that represents the proportion of each mutant in the pool across the time course relative to the reference timepoint (see Materials and Methods).
Indeed, a generic plasma membrane protein that is excluded from the CSD in wild type (Alassimone et al., 2010) shows a pattern of exclusion in the mutant that represents a perfect negative image to the CASP1-GFP islands.
Large-scale mutagenesis screens in the zebrafish employing the mutagen ENU have isolated several hundred mutant loci that represent putative developmental control genes.
Large-scale mutagenesis screens in the zebrafish employing the mutagen ENU have isolated several hundred mutant loci that represent putative developmental control genes [ 1, 2].
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