Sentence examples for mutants that reduce from inspiring English sources

RNA mutants that reduce repression were screened against libraries of randomly mutagenized L30e proteins.

Mutants that reduce neurotransmitter release are resistant to the effects of aldicarb, whereas mutants that increase neurotransmitter release are hypersensitive.

Prp22 mutants that reduce ATPase activity compromise the fidelity of exon ligation both in vivo and in vitro [ 192].

Mutants that reduce negative feedback considerably (CDC2438A) still show competition, with dynamics similar to wild−type (Kuo et al. 2014).

Previous mouse models of Nav1.6 were limited to loss-of-function mutants that reduce neuronal firing and tend to suppress spontaneous seizures (reviewed in 12).

Furthermore, some mutants that reduce IIS extend lifespan only in the presence of Wolbachia (Gronke et al., 2010), possibly because the bacterium can attenuate deleterious effects of IIS down-regulation.

TC10 mutants that reduced AMPAR recycling had no effect on increased AMPAR levels with long-term potentiation (LTP) and little effect on decreased AMPAR levels with long-term depression.

The R620W variant of this gene is, somewhat unexpectedly, a gain-of-function mutant that reduces TCR signalling capacity.

Surprisingly, VasΔ617, a mutant that reduces the interaction with eIF5B and thus affects the role of Vas in translational activation (Johnstone and Lasko, 2004; Liu et al., 2009), also could not rescue suppression of HeT-A expression (p = 0.0024).

The enhanced auto-phosphorylation activity of the N-Srcs is reminiscent of mutants of C-Src that reduce intramolecular interactions.

We screened candidate compounds using a cell-based in vitro assay for those that reduce mutant SOD1 (G93A) protein expression.