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C. elegans mutants that influence fat metabolism often affect aging, for example, mutants in insulin/IGF and TGF-β pathways mediating the response to food signals have longer lifespans (reviewed in [4], [5]).
If there is a unique conformation of R3 DNA, we might identify mutants that influence that process.
As Asf1 is a histone H3-H4 chaperone, some Asf1 mutants that influence histone binding are sensitive to agents that induce replicative stress or DNA damage [ 23].
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First evidence for a potential role of DJ-1 in the regulation of mitochondrial morphology came from comparative studies of different generated DJ-1 mutants that influenced the oxidative modification of a critical cysteine in position 106 [106.
To identify molecular components involved in plastid development during the youngest phase of the Arabidopsis life cycle, a screen was conducted to identify mutants that specifically influence plastid development in embryos and seedling tissues derived from the embryo, but not in tissues derived from the apical meristem.
To address how DDT intermediate resolution proceeds when delayed to G2/M, we followed by 2D gel electrophoresis the fate of replication-derived damage-bypass SCJs accumulating in sgs1 mutant cells or other genetic backgrounds that influence SCJ resolution in S phase.
Such samples permit statistical inference of the population genetics parameters that influence the fate of mutant variants.
These factors probably influence the number and identity of mutants that are scored to affect growth.
This suggests that factors that influence the degree of opening on the cytoplasmic side of the triple mutant may modify the transport kinetics.
We believe, however, that there should be additional pathogen factors that influence activation of systemic immunity because Drs was not completely abolished in the single mutants, although that might have been the case in a SAP4, SAP6 double mutant.
Lastly, microarray analysis and mutant screens used in this study can only examine alterations at the RNA and DNA level that influence L-form formation and survival.
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CEO of Professional Science Editing for Scientists @ prosciediting.com