Sentence examples for mutants that improve from inspiring English sources

This dataset contains GALR3 point mutants that improve recombinant protein expression and thermal stability of the receptor contained in virus-like particles (VLPs) or obtained by detergent-purification of baculovirus-infected insect cells.

In our experience mutations that improve fluorescent brightness are much more readily identified than mutants that improve photostability.

Maranas and colleagues have previously applied mixed integer linear programming (MILP) to design mutants that improve byproduct yield or identify "minimal reaction sets" that are capable of sustaining a given biomass optimum [ 24, 25].

It may be beneficial to exploit the molecular "barcodes" of yeast mutant collections and microarray-based methods (reviewed in Smith et al. 2010) to identify mutants that improve either recombinant XI/XK or XR/XDH/XK xylose fermentation in anaerobic batch cultures that better replicate industrial-scale biofuel production.

Surprisingly, we identified four deletion mutants that improved xylose consumption of laboratory S288C, even in the absence of exogenous XYLA.

Three known antibiotic substrates of AcrB [ 29] of varying molecular weight – nalidixic acid (232.24 g mol-1), chloramphenicol (323.13 g mol-1) and tetracycline (444.44 g mol-1) – were chosen to investigate the antibiotic resistance of the mutants that improved n-octane efflux (i.e. 1G1, 1G2, N189H, T678S, T678A, Q737L, M844L and M844A).

To facilitate rapid selection of improved AcrB from the enriched libraries in the absence of a high-throughput method for measuring efflux rate of n-octane, the enriched libraries were preliminarily assayed as variant mixtures to identify the pools with AcrB mutants that improved extrusion of n-octane.

In contrast to these mutations that led to a decrease in the specificity of the ERK2-Ets interaction, the modeling also allows for a prediction of potential mutants that might improve specificity.

We performed a "chemical suppression" screen by using a previously described collection of temperature-sensitive (TS) mutants (Li et al. 2011) and sought those mutants that showed improved growth in the presence of HU at the otherwise-restrictive temperature where the mutant would normally fail to grow.

While our results suggest that improved drug efflux mutants should not have a fitness advantage when they are at low levels in a QS-inhibited population, Wood and co-workers showed that improved-efflux mutants (via overexpression of the MexAB-OprM drug efflux pump) were able to readily spread under C-30 treatment.

Thus, the mutant colonies appearing under selection may reflect preexisting small-effect mutants that adapted and improved during colony growth.