Sentence examples for mutants that generated from inspiring English sources

Most importantly, we observed that the GSS-associated mutants that generated significant levels of CyPrP and prevented condensed chromatin could not prevent caspase activation.

We also identified a number of cell lethal mutants that generated wild type twin spots but no apparent corresponding mutant clone, implying that recombination had occurred but that the mutant cells did not survive.

We further examined five potential off-target sites from three groups of F1 white-eyed mutants that generated from Cas9 nickase and pairs of sgRNAs.

The results show that CyPrP generated from GSS PrP mutants does not aggregate in the cytosol and thus, aggregation cannot be responsible for the loss of anti-Bax function in the GSS mutants that generate CyPrP.

A major challenge in studying achiasmate chromosome segregation mechanisms is that most of the mutants that generate natural nonexchange chromosomes have very poor spore viability.

The APCMin/+ mutation, which results in high levels of β-catenin, predominantly causes intestinal polyposis, while APC mutants that generate intermediate levels of β-catenin preferentially induce mammary tumors [ 95].

No differences in splice site scores were observed between wild-type and 648T>A or 1250C>T transcripts or between wild-type and mutant transcripts that generated low exogenous protein expression.

The study of mutants to elucidate gene functions has a long and successful history; however, to discover causative mutations in mutants that were generated by random mutagenesis often takes years of laboratory work and requires previously generated genetic and/or physical markers, or resources like DNA libraries for complementation.

It increased the number of mutants that were generated in comparison with the manual generation of code, that only contains the essence of an embedded system model.

As the disease advances, the chances of treatment failure rise due to the presence of drug resistant mutants that are generated mostly through point mutations [11] [16].

As the disease advances, however, the chances of treatment failure rise due to the presence of drug resistant mutants that are generated mostly through point mutations, but also through gene duplications [5], [6], [8] [15].