Sentence examples for mutants that fail from inspiring English sources

Furthermore, we studied DNA binding by MvaT mutants that fail to repress gene expression in P. aeruginosa because they are specifically defective for higher-order oligomer formation.

Since few mycobacterial proteins have so far been directly implicated in the interactions between M. tuberculosis and host cell apoptosis, we screened M. tuberculosis H37Rv transposon mutants to identify mutants that fail to inhibit cell death (FID).

Meanwhile, in Szostak's lab, Lundblad identified the first known subunit of telomerase--a protein she dubbed Est1--by laboriously screening for yeast mutants that fail to maintain their telomeres, a novel approach at the time.

Indeed, MyoD deletion mutants that fail to interact with Runx1 do not interact neither with CBFβ.

Furthermore, in Drosophila, cid mutants, that fail to assemble the kinetochore, show a BubR1-dependent early mitotic delay [31].

Such a phenotype is characteristic of nuclear exosome mutants that fail to degrade aberrant nuclear RNAs [39].

Microarray data comparisons for each growth condition allow the identification of mutants that failed to survive the imposed growth selection.

Mutants that failed this test were considered "non-viable" and discarded.

The remaining SYT-SSX2 mutants that failed to be targeted to polycomb bodies had no effect on Bmi1 cellular levels.

In fact 55% (26/47) of the deletion mutants that failed to arrest in G1 following LoaOOH exposure were sensitive to DOX suggesting that defects in G1 associated checkpoint control may represent a significant proportion of the DOX resistance genes identified in the diploid yeast screen.

Furthermore, we identified a set of transduction mutants that failed to perform magnetic orientation.