Sentence examples for mutants such that from inspiring English sources

The observed predominance of positive epistasis among viral genomes suggests a buffering effect for subsequent mutants such that the mutant spectrum is enlarged [25], [46], [47].

However, this approach will ensure the same start point for all mutants such that factors associated with bacterial fitness in the middle ears are equally represented in the screen procedure.

Therefore, ingroup favoritism does not occur, i.e., ρ = 0. Furthermore, the population of DISC players is invaded by ALLC mutants such that it is unstable.

Edema also resolved in around half of the mutants such that larvae were morphologically normal, apart from a failure to inflate swim bladders.

Thus, a net reduction in protein translation may reduce the levels of misexpressed intestinal proteins in lin-35 ; slr-2 and dpl-2 slr-2 mutants, such that their negative impact on intestinal functions is diminished.

However, in this revision we used the same reference strain to quantify the fitness of the clinical isolates and the deletion mutants, such that that results in Figure 7A and Figure 8 can be readily comparable by the reader.

One is that inactive Sulf-2 acts as a "substrate trapping mutant" such that it competes with the active enzyme for binding to heparan sulfate substrates, thereby blocking the ability of the enzyme to alter the substrate and modulate Wnt interactions.

Their initial "loop-less" mutant was much less stable than the wildtype, but it proved possible to "retro-engineer" stability into the mutant, such that it out-performed wildtype under chelating conditions.

If the interaction between Vps1 and actin is reduced, as in the vps1 RR-EE mutant, such that the actin network can no longer be re-organized, force will not be transduced to the appropriate scission site, thus precluding release of the vesicle.

Note that the NRPD2b gene is a pseudogene due to a frameshift mutation, such that the double mutant is used only as a precaution.

However, as ENU mutagenesis screens assay in vivo phenotypes, they can uniquely detect mutants, such as Sci, that affect the SCN intercellular network.