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If Mcm2-7 is an important cellular target of ciprofloxacin, then Mcm mutants should exist that confer ciprofloxacin resistance.
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The observed reduction in FRAP recovery times between the wild type and mutants demonstrates that a measurable assay window should exist for the displacement of wild-type BRD4 from chromatin by small-molecule inhibitors of the bromodomain.
"It should exist by now".
If rules exist, they should exist equally for everyone.
What limits and safeguards should exist?
Lawmakers could not agree on whether that authority already existed or should exist.
"Loti should exist, even if his house is closed".
Ouch! "Governments should exist to help people, not institutions".
Rather, she is solely interested in what should exist.
Companies should exist to optimize happiness, not money.
"He felt that old and new should exist together".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com