Sentence examples for mutants requires further from inspiring English sources

The pathways by which Ret signaling targets complex I and rescues Pink1 mutants requires further investigation.

7 However, given that long‐time treatment with rapamycin can also affect mTORC2 activity in some cell types, 16 whether mTORC1 is the only complex that mediates the starvation resistance of cells expressing transforming mTOR mutants requires further examination.

The modification of the E701C/E730C double mutant by oxidation/reduction requires further characterization.

The role of mutant PIK3CA in oncogenic signaling requires further investigation, including development of novel targets for therapeutic intervention in cancers harboring PIK3CA mutations.

Whether the differences in placental morphogenesis and/or maternofetal nutrient exchange between mouse and human contributes to the placental mineralization observed in Sucla2 mutant placenta is unknown and requires further investigation.

The link between folding and PM trafficking of KCNQ4 and its mutants will require further study to shed light on other co-chaperones and the mechanisms of ERAD.

This phenomenon may be related to aberrant Nav1.7 function, and the possibility of a role for mutant SCN9A in the scheme of trigeminovascular theory requires further study.

We suspect that this death may represent apoptotic death observed by others using mutant α-hemolysin, though formal demonstration of this requires further investigation.

However, the precise mechanism of the regulation of these operons requires further experiments employing for example reverse genetics to analyse null-mutants.

Our site-directed mutants corroborate these findings for the class Ia enzyme but NrdR regulation of the class Ib and class III genes requires further evaluation.

This requires further study.