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This indicates that kar mutants provide normal iridophores to rse mutant fish, and that kar is not required in iridophores.
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Our analyses of Utx mutants provide no evidence for a tumour suppressor function of Utx and show that the zygotic Utx product is dispensable for the normal development of epidermal structures but is essential for adult viability.
Nerve conduction studies provided normal results.
RG provided normal peripheral blood samples.
DHS provided normal bone marrow specimens.
Sequencing of the UV-induced lacZ′ mutants provided mutation spectra and mutational hot spots for the various UV regions.
All Sse1 mutants isolated provide essential functions in the cell under normal growth conditions, further demonstrating that essential chaperone functions in vivo can to some degree at least be detached from those related to propagation of prions.
Other methods [ 11] provide similar normal values.
Further mapping in this mutant can provide more insights regarding the causal mutation for the mutant phenotype.
We speculate that the STX11 Arg78Cys mutant will provide further insight into the pathobiology of STX11 in PTCL and will reveal novel roles of STX11 in normal T-cells.
Mutant p53 provides keratinocytes an advantage over normal keratinocytes in response to successive UVB exposure by evading cell cycle checkpoints and by allowing mutant keratinocytes to evade UVB-induced apoptosis.
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