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Thus, cldn15lb mutants provide a novel in vivo model to study the role of tight junction proteins in the remodeling of the biliary network and hereditary cholestasis.
The hopTum-l mutants provide a convenient system to test this, as the mutation is temperature-sensitive conditional.
The two mutants provide a way to monitor the effect of deleting one gene on the expression of the other gene.
These mutants provide a valuable resource for genome-wide functional analyses.
Genes which are deregulated in rx3 -/- mutants provide a novel resource to identify biological processes underpinning optic vesicle morphogenesis.
Zebrafish mutants provide a powerful tool for examining the roles of individual genes in such a network.
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Myelin mutants provide an opportunity to study neurophysiological and behavioral effects of demyelination.
In a near-isogenic state with wild type (WT) cotton these two short fiber mutants provide an excellent model system to study mechanisms of fiber elongation.
Publicly available data enable the construction of new hypotheses, and the mouse mutants provide an invaluable resource for follow-up studies.
In addition, oat mutants provide an excellent tool to investigate if mitochondrial Orn (e.g. from Arg degradation) or externally supplied Orn can be converted to Pro by alternative pathways.
The characterization of cysteine and/or alanine mutants provides a systematic screening of the contribution of each residue to CNGA1 gating.
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