Sentence examples for mutants previously reported from inspiring English sources
In addition, the effects of the dominant-negative mutants previously reported were linked to telomere shortening (due to the lack of telomere elongation) and increases in basal apoptotic rate.
As a first step to interrogating the genetic basis of withdrawal behaviour in C. elegans we investigated whether mutants previously reported to affect ethanol dependent behaviours altered responses in the food race paradigm.
To validate our in silico model we studied a panel of claudin-1 mutants, previously reported to modulate HCV entry (Cukierman et al., 2009).
Accordingly, the S. pombe mutants previously reported as long-lived are known to grow slowly, including git3Δ, gpa2Δ, pka1Δand sck2Δ (Roux et al., 2009).
We corrected all seven but found that two mutants previously reported to be recessive lethal alleles were in fact likely dominant lethal alleles and therefore could not be used in our analysis.
The closest exception to this generalization may be the laminin mutants previously reported [ 51], where germ cells were documented to be actively invading somatic tissues, in conjunction with midbody swelling.
The menC mutant, previously reported, was generated by transposon insertion using a suicide plasmid with a mini-Tn10 transposon derivative [29].
The corresponding region in human AMBN is deleted in the human AMBN−6/−6 mutation reported here and in the Ambn−5,6/−5,6 mouse mutant previously reported.
We utilized the ezrin Y477F mutant previously reported to disrupt the ezrin-Eps8 interaction in gut epithelial cells (Zwaenepoel et al., 2012).
The GABI-KAT T-DNA insertion mutant previously reported also hyper-accumulated Gol in the leaves after cold stress [4°C, 14 d; 15].
In Rab7 mutants, ∼70% of initially bound GTP dissociated over the course of 60 min. Although Rab7 disease mutants were previously reported to have nearly complete loss of GTPase activity (21), we found no structural basis for altered GTP hydrolysis in the L129F mutant.
