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Normally when thinking of artificial neural networks (ANNs), the mind's eye explodes with predictably trippy images of puppyslugs and other computer-generated mutants originating from Google's so-called Inceptionism program.
Results from this study instead suggest that transporter-mediated NO 3 - accumulation in NR deficient mutants, originating from traces of nitrate in the media, is responsible for the constitutive expression of NirA-regulated genes, and the associated phenotype is thus termed "pseudo-constitutive".
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Since the mutants originate from a directed evolution experiment and are functional, the data provide an evolutionary snapshot of how a protein structure can respond to mutations while maintaining a functional molecular architecture.
Two R118K mutants originated from successive years (2007 2008), which could indicate that this mutation was established in the wild virus population.
The clinical isolate D7S, which was used as the host strain of the tad-locus single gene mutants, originated from a 28-year-old African-American female (USA) with generalized aggressive periodontitis [31].
The identities of the selected mutants originated from ATCC 17978 were confirmed using pulsed-field gel electrophoresis (PFGE).
The ST mutant originates from cv.
At present we cannot exclude the former, but the latter would be in full accordance with the Wt1-mutant tumours originating from an earlier developmental stage.
Recently, an orange-pericarp mutant (MT) originating from Guanxi pummelo has been discovered in China and provided us a potential material for studying this regulation mechanism.
Consistent with previous reports (Subramanian & Govindan, 2008), KRAS mutations in lung cancer were strongly associated with a history of smoking (89% of KRAS mutations were found in patients that smoked >10 packs/year), while the reverse was true for EGFR, with 73% of EGFR-mutant tumours originating from patients who had never smoked.
For this purpose, we sequenced two high light (HL) resistant C. reinhardtii mutants that originated from a forward genetic approach by either spontaneous mutation or ultraviolet (UV) light induced mutagenesis, respectively.
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