Sentence examples for mutants or mutants from inspiring English sources

In vitro telomeric DNA extension occurred with extracts from wild-type yeast but not fromest2 mutants or mutants deficient in telomerase RNA.

In most bacteria that have been studied, the rpoN gene deletion resulted in viable mutants or mutants requiring certain nutrient addendum [ 8, 52, 53].

Plasmid-cured mutants (or mutants in which deletions have been introduced into the plasmid) either lose all chemolithoautotrophic growth capabilities or cannot utilize H2 plus CO2 but retain the ability of using CO plus CO2 [ 4, 25, 28].

Similarly, protein kinase CK2 phosphorylates Hsp90 on threonine 22, and phosphomimic mutants or mutants that cannot be phosphorylated destabilize client kinases and alter GR activity (Mollapour et al., 2011), suggesting that cycling between phosphorylation states is critical for Hsp90 function.

eak-7 (tm3188 ) and akt-1 (ok525 ) both harbor deletion mutations that are likely to be null alleles (Hertweck et al. 2004; Alam et al. 2010); these alleles were chosen to minimize the chances of isolating informational suppressors such as tRNA anticodon mutants or mutants defective in nonsense-mediated mRNA decay.

Then I started to think about how to design screens for serotonergic mutants and thought that perhaps some of our hindbrain patterning mutants or mutants that affect early development of specific cranial nerves might also affect serotonergic neuron development and so impact mood disorders.

The mapping of P450 expression in mutants most often highlights very specific responses in isolated mutants or mutant groups.

Whether these exceptions are truly examples of mutants that aggregate slowly and yet are associated with rapidly progressing disease (e.g. D101N mutant) or mutants that aggregate rapidly and yet are associated with slowly progressing disease (e.g. E100K) is uncertain.

The competitive index (CI) within nasal wash, nasal tissue, blood and lung samples was determined at 24 h and 48 h post-challenge on selective media by calculating the ratio of wild-type to mutant or mutant to mutant as required, relative to the input ratio.

DOI: http://dx.doi.org/10.7554/eLife.02252.004 10.7554/eLiFigure52.005 Figure 1 figure supplement 1. Overview of all heterozygous and homozygous combinations and their controls (Col x mutant or mutant x Col) obtained by crosses.

While we have used the qTags to analyze conditional knockdown mutants they are just as suitable to analyze transposon mutants, deletion mutants, or point mutants and their complemented derivatives as well as different clinical isolates in multi-strain cultures or multi-strain infections.