Sentence examples for mutants of unknown from inspiring English sources

(5) Set of random mutations: We randomly selected one mutation in each of the 28,913 proteins from the set of mutants of unknown disease relation such that the mutated position was maximally distant from any other mutation observed in the given protein.

In addition to the biosynthesis mutant affected in CYP79A1, the authors also identified three mutants of an unknown molecular nature, all of which were not affected in any of the P450s known to participate in the biosynthesis of dhurrin.

Characterization of the nine mutants of function-unknown genes indicated that some of them, such as yfgA that genetically interacts with a periplasmic chaperone gene surA together with yciB and yciM, might be required for the integrity of outer membrane.

Many mutants for genes of unknown function were much more Congo red negative than the wild-type parent (M90T-Sm) (e.g., orf185 and orf47) and some mutants for genes of unknown function were more Congo red−positive than M90T-Sm (e.g., orf131a, orf131b, and orf163).

Chemical sensitivity testing has proven to be a powerful method for identification of phenotypes for gene deletion mutants and genes of unknown function, as evident from previous studies in S. cerevisiae (Hillenmeyer et al. 2008) and our analysis of protein kinases (Park et al. 2011b).

The apparent small enhancement of NDV-GFP expression in cells transfected with either chicken Mx, murine Mx1 or the mutant K49A protein is of unknown biological relevance.

Expression of the GTP- or GDP-bound mutants of Gtr1-Gtr2 supersedes this unknown Gtr1-Gtr2-independent pathway in the regulation of TORC1 and autophagy by locking TORC1 in an activated or inactivated state irrespective of upstream signals.

The clinical relevance of Q136K mutants is unknown.

Using SGM also allows researchers to avoid mutant phenotypes from being masked due to the presence of unknown substrates, especially when testing auxotrophic deletion mutants.

Although we did not detect any differences in growth or gliotoxin production in these mutants, other unknown phenotypical characters of these color mutants could play a role during infection.

Mutant SOD1 takes on a toxic gain of unknown function.