Sentence examples for mutants of key from inspiring English sources

Further testing with additional conditions and different antibiotics as well as study with mutants of key genes will help unveil the mechanism of bioelectric effects.

Quantification of post-stimulus aggregation in mutants of key components in the cVA signaling pathway (p = 0.4405, one-way ANOVA test, n = 3 for each trial).

It is also apparent that the subtelomere compartment in the trypanosome genome differs from the chromosome cores in its interaction with recombination/repair mechanisms, becoming disproportionately disrupted in null mutants of key players MRE11 and BRCA2.

In contrast, O2 -regulated genes have been extensively studied in the model animal-associated enterobacteria Escherichia coli and Salmonella enterica, where available data includes genome-scale expression profiling of the anaerobic stimulon of wild-type strains as well as mutants of key regulators FNR, ArcA, NarPQ and NarXL [ 11- 16].

This two-gene spanning deletion generated a double mutant of key genes of lifestyle and metabolism of P. aeruginosa[ 35, 36].

To map the interacting domains, we generated in-frame One-STrEP and HA-tagged truncation mutants of the key domains of IRF5 and FLAG-tagged truncation mutants of the key domains of RelA.

The results shown in Fig. 5 also indicated that none of the mutation in the loop region of HWTX-XI influenced the inhibitory potency toward Kv1.1 channels and that the mutants of the key residues for Kv1.1 channel blockage have no effect on trypsin inhibition activities.

Consistently, nfs expression is altered in mutants of several key developmental regulators necessary for appropriate expression of sporulation genes.

SGA revealed synthetic lethality of the CCW12 deletion in combination with mutants of the key regulatory kinases of the CWI pathway, BCK1 and SLT2 (Table 1).

Six single mutants of these key residues, obtained by site-directed mutagenesis, resulted in almost completely inactive proteins, as shown in [Additional file 1].

This paper is an extension of our previous study of Physcomitrella knockout mutants of a key MRN (MRE11, RAD50, and NBS1) complex [ 6] with a pleiotropic effect on DSB repair in whole.