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Knockdown or knockout mutants of either PEZ1 or PEZ2 expression show decreased amounts of protocatechuic acid and caffeic acid, as well as decreased Fe concentrations, in xylem sap.
This strategy is rooted in the principles from yeast genetics where mutants of either two related genes are viable, but loss of both genes functioning in a redundant pathway causes cell death [76].
In maize, double mutant defective in both ISA2 and SSIII generated water-soluble glucans in the mutant endosperm, although single mutants of either ISA2 or SSIII could synthesize normal amylopectin (Lin et al. 2012).
In order to characterize the interaction between ETO and N-CoR, mutants of either protein were constructed and tested for binding in both yeast two-hybrid and immunoprecipitation assays.
Polyhydramnios, severe edema and hemorrhage are universal findings in homozygous mutants of either locus by E12.5.
We used single mutants of either outC, or hrcV and a double mutant outC/hrcV to demonstrate that DspA/E from 3937 is delivered into the plant cytosol in a T3SS-dependent manner.
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We hypothesized that we could block diphthamide formation with a dominant negative mutant of either Dph1 or Dph2.
PFO production by the strain 13 ΔagrB mutant could be restored by genetic complementation or by physical complementation, i.e. by co-culture of the strain 13 ΔagrB mutant with a pfoA mutant of either strain 13 or C. perfringens type C CN3685.
A knockout mutant of either AtNRT2-1 or AtNRT2-2 results in a reduction of iHATS; however, a double knockout is required to reduce the cHATS, suggesting partially redundant functions of these paralogs [ 62].
We adapted this assay to allow screening of mutant libraries of either l- or d-amino acid specific aminotransferases in a continuous fashion.
In the context of the delocalized Pc2 2-531) truncation mutant, deletion of either SIM alone abolished E3 activity towards CtBP (Figure 5B).
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