Sentence examples for mutants of a given from inspiring English sources

The application of GP to PCM datasets, gives the insight that GP could also be very useful in the drug discovery for personalized medicine, when the target space includes several mutants of a given target [15, 80].

In particular, there is a general lack of significant correlation of phenotypes between the heterozygous and homozygous (null) deletion mutants of a given gene.

While automated methods have been introduced to extract information about the existence of mutants of a given protein (69, 70), current content annotation and text mining technologies do not allow us to use automation to reliably extract experiment-specific, structure function information from published papers.

In general, larger values of α will result in more significant tests and thus more independent mutations will be inferred, but the number of mutants for a given lethality does not change significantly, which are mostly determined by the percentage of z/z offspring in the F3.

This indicates that the diversity graph is independent of the initial concentration of the primal source, which allows a unique graph representation of the metabolic differences of the mutants for a given growth condition.

In good agreement with this expectation, all substitutions represented at a frequency ≥ 0.2 in the mutant spectrum of a given population appeared also as double peaks in the chromatogram of the consensus sequence of the same population.

What is the expected number of mutants in a stochastically growing colony once it reaches a given size, N? This is a variant of the famous Luria Delbruck model which studies the distribution of mutants after a given time-lapse.

However, it is not easy to decide the proper fractions to use, so a conservative approach was taken by removing all families with a percentage of mutants exceeding a given threshold value.

Probability generating function is used to study the probability of colony extinction, probability of treatment success, and the probability of having resistant mutants at a given colony size.

As a result of drawbacks in currently used reverse genetic techniques, the pace of research into biological processes in C. elegans is still largely dictated by the probability of obtaining a mutant of any given gene and, thus, new techniques are needed to complement those previously described.

Based on the hypothesis that metabolic products are exchanged in a bacterial population, we previously developed a graph-theoretic approach (diversity graph) in order to map pair-wise genetic to metabolic alterations with respect to by-production and identify communities of metabolically different mutants in a given environment [ 32].