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In contrast, the onset of ectopic expression of P granules in lin-35; lsy-2 double mutants occurred much earlier.
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However, he found it occurred "much sooner than I anticipated".
His passing has occurred much too early.
Severe thrombocytopoenia (13%) and anaemia (2%) occurred much less frequently.
Uncontrolled asthma occurred much less frequently than controlled asthma.
Conserved motifs for other ubiquitous factors occurred much less frequently.
However, in other lineages, rearrangements have occurred much more rapidly.
Coalescent events occurred much earlier in mtDNA than in cpDNA.
However, peak induction occurred much earlier (1 hour) and was much higher (108-fold).
On the other hand, failure of cell-cycle exit could activate p53, even though p53 activation occurs much earlier than cell-cycle exit in the shh−/− mutant retina (Figs. 5, S2).
Obviously, any neuronal loss inflicted by APP.SLA is much less, or occurs much slower than the intense, rapid pyramidal neurodegeneration provoked by wild-type and mutant tau in this paradigm.
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