Sentence examples for mutants may activate from inspiring English sources

Taken together, we found that wild-type FGFR3 as well as G380R, R248C and Y373C mutants may activate STAT1 depending on the cellular environment, although this activation is significantly lower when compared to K650M or K650E-FGFR3 (Fig. 2).

With further genetic engineering these mutants may activate alternative hexoses as GDP-sugars for transfer to aglycones in vivo.

Increased UBD has also been positively correlated with mutant p53 expression, which may activate UBD expression and indirectly facilitate gastric cancer progression (Zhang et al, 2006; Ji et al, 2009).

Even spontaneous membrane oscillations may activate these mutant channels.

These results suggest that despite many similarities in their oncogenic capacity, the different mutant forms and Ras overexpression may activate also distinct downstream targets that are responsible for the different oncogenic capacities.

Interestingly, Ca2+ can rescue the temperature-sensitive growth of C. glabrata calcineurin mutants at 40°, indicating that Ca2+ may activate a specific signaling cascade that supports growth at an elevated temperature.

An alternative model is that 18∶0 (which accumulates to high levels in fat-6;fat-7 mutants), or a signal derived from it, may activate NHR-64 to promote increased fat oxidation in peroxisomes.

Since the functional activity of the tyrosine kinase domain is impaired in this class mutant allele, our results strongly suggest that Klotho may activate DAF-16 by a different pathway from the canonical worm DAF-2/DAF-16 signalling cascade.

Based on the current model of sphingolipid synthesis regulation, we expect that reduction of the complex sphingolipid M IP 2C in vps53Δ cells may activate the upstream sphingolipid synthesis enzyme SPT by releasing Orm1/2 inhibition, thereby exacerbating the GARP mutant phenotype.

An arrest may activate the clause, or only a conviction.

RONS may activate AMPK by direct an indirect mechanisms.