Sentence examples for mutants link to from inspiring English sources

Structural models of protein mutants link to candidate SNPs that alter arsenic responsiveness were generated using MODELLER 7v7 39 with appropriate homologous high resolution X-ray crystal structure templates from the Protein Data Bank (PDB).

Structural and biophysical studies of PCSK9 and its mutants linked to familial hypercholesterolemia. Proprotein convertase subtilisin kexin type 9 (PCSK9) lowers the abundance of surface low-density lipoprotein (LDL) receptor through an undefined mechanism.

Seven mutants linked to an identical cardiac edema phenotype mapped in the same region of Chromosome 6 between 67 and 71 Mbp.

(D ) Tsr2 interacts with eS26 mutants linked to DBA.

Thus, eS26 mutants linked to DBA are impaired in cytoplasmic processing of 20S pre-rRNA.

(C ) eS26 mutants linked to DBA accumulate 20S pre-rRNA in the cytoplasm.

More studies need to be conducted to determine whether the LMNA mutants linked to progeria affect the function of scaffold nucleoporins.

These data provide a much needed map of the phenotypic complexities due to overexpression of various TDP-43 alleles, including wild-type and several mutants linked to ALS.

The remaining functional categories comprise mutants linked to metabolism (principally of RNA and proteins) and other cellular functions with lower representation in the screening (see Table 1).

Unreduced gamete-producing mutants linked to defects in the meiotic cell cycle machinery have also been recently identified in model plant Arabidopsis thaliana, leading to greater understanding of the mechanisms behind unreduced gamete formation [ 5].

A 24-bp in-frame deletion in domain TB5 linked to Weill Marchesani syndrome and missense mutants linked to the geleophysic and acromicric dysplasias have been reported to alter the interactions of this region of fibrillin-1 with heparan sulphate (43).