Sentence examples for mutants lacking one from inspiring English sources

Since the disordered N-terminal region of BCNT contains an acidic stretch (14 acidic aa in region of aa 71 92; 64%), including stretches of seven and five consecutive acidic aa residues, we evaluated the effects of this acidic stretch on SDS/PAGE mobility by generating three deletion mutants lacking one or both acidic aa stretches.

Clues have come from studying the expression of oxidases in response to growth conditions, the phenotypes of mutants lacking one or more oxidases, and biochemical characterization of individual oxidases.

In this study, we investigated the contribution of each particular disulfide to the folding, stability and function of LCI by constructing a series of single and multiple mutants lacking one to four disulfide bonds.

An example is the finding that mutants lacking one of several genes in the folate biosynthetic pathway are hypersensitive to ZEB, leading to a demonstration of synergy between trimethoprim and ZEB.

In addition the two single mutants lacking one of the stearoyl-CoA desaturase genes showed differences in their fatty acid content.

Mutants lacking one pigment cell type, nac (A and A′ ), pfe (C and C′ ), and shd (E and E′ ), only form remnants of the pigmentation pattern.

An alternative way to quantify the extent of divergence/redundancy of duplicated genes is to examine phenotypes of of null-mutants lacking one of them.

These libraries consisted of 647 mutant strains lacking one of the essential virulence genes [ 15], 96 cell wall protein mutants [ 42], and 165 transcription factors mutants [ 43].

In addition, gsk-3β haploinsufficient mutant mice, lacking one copy of the gene coding for GSK-3β, show the same behavioral effects as lithium-treated mice (O'Brien et al. 2004).

Such variation of -σ is carried out within three genetic backgrounds – the wild type E. coli and two mutant strains lacking one of the two abundant DNA architectural proteins, either FIS or H-NS.

For example, part of the biosynthetic pathway for jasmonic acid occurs in the peroxisomes and a mutant line lacking one of the enzymes involved in this process in Solanum lycopersicum is impaired in its ability to mount defence responses against some insects [ 39].