Sentence examples for mutants it appears from inspiring English sources

Additionally, because high doses of metformin can result in reduced lifespan in eat-2 mutants, it appears that when an animal is already in the DR state, further stimulation of DR physiology by metformin leads to diminishing, even harmful, effects, a phenomenon typical of extreme calorie limitation or starvation in C. elegans [34] [36], [39] and mammals [49].

While the ensuing reduction in cell numbers undoubtedly contributes to the abnormal hindbrain development in kto/med12 mutants it appears unlikely that it can explain the specific loss of rhombomere boundaries, which are more likely due to impaired segmental identity in the mutant hindbrain.

Based on our complementary results from three different mutants it appears that TA is closely linked to IXB but more distantly related to DCB [ 12].

Since the eoplast to chloroplast transition is defective in sco1-1 and sco1-4 mutants, it appears that SCO1 activity is particularly critical during either the transition from chloroplast to eoplast, or when eoplasts redifferentiate into chloroplasts after germination.

Compared to other mutants, it appears that this combination results in the least drastic effect on protein activity and stability, allowing its maintenance in the absence of insecticide selection.

Although much lower than the activation induced by K650M or K650E mutants, it appeared to be dependent on the transgenic FGFR3-activity, since we found no STAT1 Y701) activation in cells transfected by the kinase-inactive K508M-FGFR3 mutant.

When comparing sizes of colonies obtained by transformation of ynd1Δ cells with E4orf4 and the various Ynd1 deletion mutants, it appeared that the three N-terminal deletion mutants could transduce the E4orf4 signal at least partially, whereas the short 371-Ynd1-531 and 468-Ynd1-531 mutants did not efficiently transduce the signal (compare the sizes of individual colonies).

When we analyzed DNA fragmentation in DA1-3b cexpressingssing RIP3-WT and the various mutants, it appeared that only cells expressing RIP3-KD showed typical DNA ladders 10 h after induction, suggesting that RIP3 lacking kinase activity induced apoptosis in DA1-3b cells.

In rad mutant, it appears to be either directly acting as a repressor or interacting with MYB and other factors to repress the coleoptile elongation.

In the Inpp4awbl mutant, it appears that Eaat4 is protective of Purkinje cell.

Since most BR-regulated genes were normally expressed in the exo mutant, it appears that EXO does not generally affect BR sensitivity and BR levels in the shoot.