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These findings indicate that the higher nitrate content in the nlp7 mutants is caused by the reduced nitrate assimilation, rather than altered nitrate uptake.
However, we cannot rule out the possibility that the leaf variegation in the z3 mutants is caused by the citrates by themselves.
To confirm that the male sterile phenotype in our mutants is caused solely due to disruption of Ntl, we generated P-element-based constructs for germline transformation with CG7075/Ntl.
If dominant-negative inhibition of proinsulin export by co-expressed MIDY mutants is caused by recruitment of proinsulin-WT into abnormal disulfide-linked protein complexes, then a selective defect in recovery of native proinsulin-WT would be expected under nonreducing conditions.
The Daf-c phenotype of these mutants is caused by DA deficiency and can be rescued by supplying exogenous DA.
Taken together, these results disfavor the idea that the Mrt phenotype of the nuclear RNAi-defective mutants is caused by DNA mutations.
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The authors should provide some thoughts on how they think reactions with H2O2 (in the His mutants) is causing the heme to be released or degraded?
Here we show that the defects in sputnik mutants are caused by mutations in cadherin 23 (cdh23).
Thus, we conclude that the low availability of asparagine in gs1 2 mutants was caused by the reduction in glutamine content, which is required for the up-regulation of OsAS1 expression.
Our results strongly support that familial FSGS associated with TRPC6 mutants are caused by podocyte dysfunction.
This is consistent with tetraploidy in Slbp mutants being caused by prolonged arrest at the spindle checkpoint due to damage to the genome.
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