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Results showed that the mutants induced by EMS had higher survival and growth rates compared to UV mutants.
Such intermediate or leaky waxy mutants were frequent among mutants induced by a chemical mutagen, EMS.
ScQ14 is also deleted in ISS mutants induced by γ irradiation (Zluvova et al. 2007), but not in ISS mutants in this study.
Mutation spectrum analysis showed that the types of CD59 mutants induced by crocidolite fibers were similar to those induced by equitoxic doses of H(2 O(2 O
Furthermore, DNA polymerase mutants induced by prolonged or repeated therapy with vidarabine or foscarnet are often resistant also to combination therapy with existing compounds [ 8- 10].
In rice, a collection of over 40,000 mutants induced by various chemical and irradiation strategies was developed in the indica rice cultivar IR64 [ 6].
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We have sequenced the genomes of yeast mutants induced in diploids by expression of the gene for PmCDA1, a hypermutagenic deaminase from sea lamprey.
None of the GSS-associated PrP mutants induced cell death assessed by condensed chromatin in primary human neurons (Fig. 5A).
A large variety of Nod factors was produced by the three mutants when induced by apigenin or salt stress, and also in the absence of any inducer.
This suggests that the formation of a preorganized metal-binding site – existing in the wild-type enzyme but not in the W464 mutants – was induced by Im7.
The flo-1 and flo-2 mutants were induced by MNU treatment of the rice cultivar Kinmaze and their loci were localized to chromosomes 5 and 4, respectively (Satoh and Omura1981; Kaushik and Khush1991).
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