Sentence examples for mutants in two from inspiring English sources

Insertion mutants in two genes with yet unknown function, however, were found to attain significantly improved riboflavin titers and yields.

We tested this hypothesis in a Drosophila feeding infection model employing kerV ortholog knockout mutants in two γ-Proteobacteria pathogens: V. cholerae and Y. pseudotuberculosis.

Interestingly, mutants in two anti-toxin genes (Rv0596c and Rv1962) were identified as having reduced fitness at the fast growth rate.

Immunoprecipitation experiments demonstrated that as expected the CK− p27 mutants did not bind the CDK2 protein (Figure 3B) and the analysis of protein stability in the presence of cycloheximide demonstrated that the CK− mutation did not alter the stability of p27T198A/G mutants in two different cell lines (Figure 3C and Figure S3).

We analyzed the alkylation sensitivity of anc1Δ in combination with rev3Δ or rad30Δ, mutants in two translesion DNA polymerases involved in PRR: REV3 (with REV7) encodes DNA polymerase ζ, an error-prone polymerase, and RAD30 encodes polymerase η, a polymerase that is sometimes characterized as error-prone, and sometimes as error-free depending on the type of lesion being bypassed [38].

The mutations occurred in cis (double mutants) in two probands and in trans in one proband.

These are used to demonstrate that an active variant can be selected from a background of 10,000 inactive mutants in four rounds of selection and amplification.

First, we considered a training database of 339 mutants in nine different proteins and optimised the set of parameters and weighting factors that best accounted for the changes in stability of the mutants.

Here, we systematically investigate the behavior of these disease mutants in four different cell types: three not containing desmin or the related IF protein vimentin and the standard fibroblast line 3T3, which has an extensive vimentin system.

Complementation failed to restore the S phenotype in mutants in four of these ORFs.

Here we report our identification of 24 conditional mutants in thirteen different essential C. elegans loci.