Sentence examples for mutants in mouse from inspiring English sources

We also compared two approaches to measure the relative abundance of mutants in mouse lungs.

To test the contribution of SurE, Pcm, NlpD and RpoS to Y. pestis pathogenesis, we evaluated the virulence of Kimberley53-deletion mutants in mouse models of bubonic plague (s.c. infection) and pneumonic plague (intranasal infection).

These authors investigated the generation and the turnover of Q212P and others mutants in mouse neuroblastoma N2a cells discovering an intracellular post ER control pathway that selectively routes aberrant PrP species to the lysosomes [48].

Cozzolino reported a similar high rate of aggregation of these mutants in mouse NSC-34 cells.

Microinjection of ALS-FUS mutants in mouse motor neurons also causes a significant shortening of mitochondria, a feature that is similarly observed in other ALS models (21, 28).

The International Gene Trap Consortium (IGTC) (www.genetrap.org) uses gene-trap technology for high-throughput mutagenesis to produce null mutants in mouse ES cells (Nord et al. 2006).

Jander, G., Rahme, L.G. & Ausubel, F.M. Positive correlation between virulence of Pseudomonas aeruginosa mutants in mice and insects.

These worms have similar phenotypes to ANCL patients and also to CSP mutants in mice, in terms of reduced lifespan, progressive neuronal dysfunction and neurodegeneration [72].

For this purpose, we analyzed the intracellular replication of single and double RibH mutants in a macrophagic cell line and the persistence of these mutants in mice.

Drosophila infections were superior to in vitro growth assays in predicting reduced fitness of mutants in mice.

Similar to null mutants in mice, some embryos display a SAN block and a dramatic lowering of the heart rate.