Sentence examples for mutants in four from inspiring English sources

These are used to demonstrate that an active variant can be selected from a background of 10,000 inactive mutants in four rounds of selection and amplification.

Here, we systematically investigate the behavior of these disease mutants in four different cell types: three not containing desmin or the related IF protein vimentin and the standard fibroblast line 3T3, which has an extensive vimentin system.

Complementation failed to restore the S phenotype in mutants in four of these ORFs.

Because complex mechanisms control ciliogenesis, we analyzed the requirement of cilia for Axin2 expression in mutants in four genes that affect different aspects of IFT.

To evaluate T3SS factors, we tested GI colonization and neutropenia-induced dissemination of both deletional (PAO1 and PAK) and insertional (PA14) mutants in four genes in the P. aeruginosa T3SS, exoS or exoU, exoT, and popB.

Insertion mutants in two genes with yet unknown function, however, were found to attain significantly improved riboflavin titers and yields.

First, we considered a training database of 339 mutants in nine different proteins and optimised the set of parameters and weighting factors that best accounted for the changes in stability of the mutants.

Here we report our identification of 24 conditional mutants in thirteen different essential C. elegans loci.

We tested this hypothesis in a Drosophila feeding infection model employing kerV ortholog knockout mutants in two γ-Proteobacteria pathogens: V. cholerae and Y. pseudotuberculosis.

Interestingly, mutants in two anti-toxin genes (Rv0596c and Rv1962) were identified as having reduced fitness at the fast growth rate.

Among the mutants tested were a type III secretion mutant (pscD), mutants in three different type III virulence effectors (ExoT, ExoU, and ExoY), an exoTUY triple mutant, a mutant in a secreted exotoxin (toxA), and two mutants in a gene involved in the production of toxic hydrogen cyanide (hcnC).