Sentence examples for mutants have substantial from inspiring English sources

However, in our case, it is possible that the expression profiles of the long-lived mutants have substantial differentiation compared to that of the wild type.

All of the mutants had substantial Mor binding as shown in the representative gels presented in Figure 4. Previous DNase I footprinting analysis showed that Mor alone protected Pm positions from −56 to −33 from digestion by DNase I (Artsimovitch et al. 1996; Kahmeyer-Gabbe and Howe 1996; Ma and Howe 2004).

On the contrary, the mutant has substantial fluorescence signal in this range, which increases with protein concentration.

It was gratifying that it was possible to recapitulate State 2 in silico by introducing disulfide bonds at Glu-260 and Ile-270 in the JM and upper TMD helix locations because this mutant had substantial constitutive activity experimentally [ 44].

OFD-affected individuals and ta mutants both have substantial skeletal defects (Abbott et al., 1959, 1960; Gorlin et al., 1990).

We observed that exo1∆ rad8∆ double mutants have a substantial increase in MMS sensitivity, as does the mre11∆ exo1∆ double mutant.

Shh mutant s were described to have substantial enteric neurons, suggesting that it inhibits enteric progenitor proliferation (Ramalho-Santos et al., 2000).

-wrap-foot> Biochemicandand gene-silencing approaches have identified many of the ERAD components indicated in Fig. 4, but have also demonstrated that modification of their activity might have substantial consequences on the fate of processing mutants.

The HCM/DCM mutant Arg975Trp has profound effects on the binding of metavinculin to actin [7], indicating that this mutation, which is positioned within α-helix H1', should have substantial consequences on metavinculin structure.

Mr. Putin, you have substantial achievements.

So companies now have substantial foreign shareholders.