Sentence examples for mutants have significant from inspiring English sources

Single substitutions of the T64, Y78, T141 and K215 residues to alanine revealed that all mutants have significant loss of activity compared to the wild-type enzyme (Fig. 3C).

In NH4Ac chemotaxis assays odr-1 mutants have significant defects only in odorant assays (Fig. 2B).

Whereas wild-type animals nearly lack these accretions, uev-1 mutants have significant numbers of them (Figure 2G).

In particular, inactivating mutants have significant effect on endocytic trafficking and signaling [5] [7], [9], [14], [15].

Many of the long-lived worm, fly, and mouse mutants have significant changes in adiposity, as do flies selected for postponed senescence [9], [16] [19].

Although we did not see statistically significant changes in gene transcript levels between CQ-treated and non-treated, our GO functional enrichment analysis showed that CQ-treated mutants have significant enrichment in glycerol and polyol metabolic processes in both mutant parasites, and enrichment of iron/cation transport activities in the double mutant.

In the present study, low dosages of TsPOx and its mutants had significant enlarging effects on the bread loaf volume, but high dosages of enzymes didn't.

Similarly, none of the mutants had significant effects on +1 PRF (1.2 fold or less).

Our results showed that the two pfcrt mutants had significant increase in transcription levels of many genes that were related to parasite invasion and growth, although some of the responses might be non-specific to the two pfcrt mutations.

Both mutants had significant residual levels of immobile synaptic GABAA receptors and post-synaptic currents.

Furthermore, cycD mutants had significant repression of catalase and peroxiredoxin transcripts, both enzymes involved in ROS neutralization.