Sentence examples for mutants have shown from inspiring English sources

Scientists at the UN and the International Atomic Energy Agency have bombarded plants with gamma rays; three of the resulting mutants have shown resistance in the laboratory to Black Sigatoka.

Lastly, genetic approaches utilizing Chlamydomonas IFT mutants have shown how the loss of specific subunits perturb the complexes and, in the case of IFT A, they have revealed a core subcomplex containing half of the A subunits.

Previous studies on zebrafish PKD mutants have shown that disruption of the structure or motility of cilia results in pronephric cyst formation [2], [13].

As one example, studies with zebrafish mutants have shown that the zinc finger protein Prdm1 (also known as Blimp1) is required for formation of the first population of slow MyHC-expressing myocytes that form during development [1], [2].

At the same time both mutants have shown normal activation of JAK2, MAPK and STAT3 signalling, and microarray comparison with mice harboring complete GH receptor deletion showed most GH-regulated transcripts do not involve STAT5 signalling.

Based on our findings, we propose that the toxicity of WT α-syn exhibits a U-shaped toxicity profile against palmitate and other lipids/sphingolipids. Biochemical analysis of lipid extracts from the elo2Δ and elo3Δ mutants have shown that these mutants fail to synthesize VLCFAs and have defects in sphingolipid metabolism [27], [54].

Analysis of Cerl−/− Lefty1−/− compound mutants has shown that the AVE does this via the inhibition of Nodal signalling [22].

The characterization of individual bri1 mutants has shown that both the extracellular and cytoplasmic domains of BRI1 are important to its proper functioning.

Analysis of developmental mutants has shown that ovule morphogenesis relies on tightly regulated genetic interactions that can serve as a model for developmental regulation.

Interestingly, a phenotypic analysis of the znuK and znuL mutants has shown that these genes are essential for growth under zinc starvation, suggesting that C. crescentus uses these TonB-dependent outer membrane transporters as key zinc scavenging systems.

Similarly, the creation of UDP-GlcNAc pyrophosphorylase (TbUAP) and glucosamine 6-phosphate N-acetyltransferase (TbGNA1) conditional null mutants has shown that UDP-GlcNAc is also essential for bloodstream form T. brucei (Marino et al. 2011; Stokes et al. 2008).