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Therefore, the mutants have considerable potential for applications involving benzopyrene degradation.
The results presented here suggest that the inactive mutants have considerable differences in their tertiary structure around the tryptophan residues, possibly in both the NS2 and NS3 subdomains, in addition to the loss of auto-catalytic activity observed.
Similar(58)
The TH p.Phe375Leu and p.Ala376Val had significantly decreased solubility, but it was not dramatically reduced and the mutants had considerable remaining activity and only slightly altered thermal inactivation rates.
Because the F4A mutant was found to have considerable tolerance against proteinase K, the possibility that this is due to protein degradation is not likely.
The mutant PXN appear to have considerable gain of function.
Foxc1-null mutants have also been reported to have considerable brain hemorrhaging toward the end of gestation that is largely limited to the forebrain region (Grüneberg, 1943; Kume et al., 1998).
These trans-acting ATs may have considerable potential for regioselective production of modified polyketide antibiotics if they can be used to complement mutant biosynthetic assembly lines in which the natural cis-AT domains of targeted modules have been inactivated.
The states have considerable autonomy.
The Senate Democrats have considerable challenges.
The clearinghouses have considerable clout in Washington.
Many of them have considerable compulsory power.
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