Sentence examples for mutants for functional from inspiring English sources
This study provides an easy and effective approach by using the CRISPR/Cas9 system for generating loss-of-function mutants for functional genetic studies of locusts and for managing insect pests.
The major limitation of using mutants for functional genomics research is the absence of detectable (visible) phenotypes for most mutants even when the disrupted gene(s) in a mutant line is known.
To obtain phosphorylation-deficient mutants for functional experiments, we created three DDX3X mutants.
Previous studies have shown the effectiveness of using FN mutants for functional studies and genome-wide analyses.
Moreover, we demonstrated the value of these mutants for functional studies through the recovery of specific genomic copy number changes linked to interesting (and potentially beneficial) phenotypes.
The high proportion of phenotypic deviations and the wide range of abnormalities observed among the transformants suggests that mutagenesis by gene-disruption library transformation is a useful strategy to establish a highly diverse population of Physcomitrella patens mutants for functional genome analysis.
MapMan is a useful tool to provide global views of diverse aspects of high-throughput data and can be used to functionally classify rice genes with flanking sequence tag (FST) mutants for systematic functional studies (Thimm et al. 2004; Usadel et al. 2009; Jung and An 2012).
Such data would also largely contribute to validating the interest of our mutant population for functional genomics in flax.
The advantages of studying Arabidopsis include its known genome, easy transformation and available mutant resources for functional studies.
To dissect the biological function of canola CIPK genes, we constructed transgenic Arabidopsis lines heterologously expressing BnaCIPK24 gene in the sos2-1 mutant background for functional complementation test.
The amino acid residues mutated in individuals with FSGS are conserved between human Myo1e and yeast Myo1, which allowed us to introduce equivalent mutations into yeast myosin and use the resulting mutant strains for functional analysis.
