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In Arabidopsis, mutants for all five DELLA paralogs still show basal levels of fertility in the Landsberg erecta (Ler) ecotype, indicating that DELLA activity in Ler is not essential to maintain fertility (Dill and Sun 2001; Fuentes et al. 2012).
Regarding the numbers of mutants for each group of operators (columns four to six in the table), we can observe that changes applied to pointcuts (i.e. operators from G1 group) yield the largest number of mutants for all systems except for FactorialOptimiser.
As the combination of chemical inhibitors for all three MAPK pathways reproduced the LT-induced phenotype in lung epithelial cells, mutants for all six, LT-targeted MKKs were prepared.
To analyze the functional role of PEGs during seed development, we obtained T-DNA insertion mutants for all genes.
Here, we generated Drosophila mutants for all of the eight snx members, and identified Drosophila SNX3 (DSNX3) as an essential molecule required for Wg secretion.
Reduced accumulation that is increased by FTC is present to varying degrees in the 482G and 482T mutants for all of the substrates.
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We used rad2Δ mutant for all Rad2C65Δp overexpression related experiments through this study.
(c) Box plot comparing siRNA expression between WT and hrde - 1 mutant for all genes and genes with hrde - 1 -dependent mRNA changes.
Hahn and colleagues recently highlighted that, by using a YAP1 mutant for all LATS1 phosphorylation sites (5SA) including the inhibitory S127-YAP1 phosphorylation, while permissive, required additional phosphorylation of Y357-YAP1 by the SRC family kinase (SFK) YES to activate transcription [ 16].
In contrast, the IC50 of the I117M + H275Y variant was not substantially different from that of the H275Y mutant for all of the NAIs, further demonstrating the lack of effect of the I117M mutation on NAI sensitivity.
These combinations included grains produced from plants that were wild-type for all three SBEIIa_A, B and D genes (ABD), double mutant for SBEIIa_B and SBEIIa_D (Abd), double mutant for SBEIIa_A and SBEIIa_D (aBd), double mutant for SBEIIa_A and SBEIIa_B (abD), or mutant for all three genes (abd).
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