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The style in these mutants fails to acquire radial symmetry showing that IND and SPT are required to ensure radial symmetry establishment at the gynoecium apex.
Scx has an established role in later stages of epiblast maturation: from around E6.5 the epiblast of Scx mutants fails to develop further and does not properly epithelialize.
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Interestingly, tumor-associated p53 mutants fail to inhibit G6PD.
These mutants failed to transform chicken embryo fibroblast cells [32].
While the mutants failed to replicate in macrophages, a robust proinflammatory cytokine response, equivalent to that of the parental LVS, was elicited.
CaP axons in topped mutants fail to enter the ventral myotome at the proper time, stalling at the nascent horizontal myoseptum, which demarcates dorsal from ventral axial muscle.
However, mutants failed to significantly sensitize cells to FasL (Fig. 3C).
ceh-36 null mutants fail to respond to any AWC-sensed odorants [21], [22], [23].
Next we wanted to determine why the MORN1-KO mutants fail to grow.
crinkled mutants fail to properly develop the flies auditory organs and they are deaf [30], [31].
Additionally, a subset of MEN1-associated missense point mutants, fail to undergo DNA damage dependent phosphorylation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com