Olfr78 mutants fail to increase ventilation in hypoxia but respond normally to hypercapnia.
Finally, genetically altered organisms (mutants) fail to synthesize certain enzymes in an active form.
ChePep mutants fail to colonize the gastric glands of mice and are completely outcompeted by normal H. pylori.
In monocultures, ∆eps and ∆tasA mutants fail to form pellicles, but, facilitated by cooperation, they succeed in co-culture.
The glyS mutants fail to make ribonucleic acid (RNA) when depleted of exogenous glycine in strains which are RC str) but do so when the cells are RC rel).
Afh mutants over-estimated (under-reproduced) the timing for the longer stimulus (i.e., 30 sec). in LD condition (Fig. 4e), suggesting that mutants fail to independently process two intervals similar to PD-related timing disruption in these conditions.
The relative ease with which one can now generate targeted lesions within the zebrafish genome and widespread adoption of these approaches by the community has generated substantial evidence that many loss-of-function mutants fail to recapitulate morpholino-induced phenotypes56.
Interestingly, tumor-associated p53 mutants fail to inhibit G6PD.
In addition-and in contrast to the wild type protein-these LKB1 mutants fail to activate the GSK-3beta kinase, which otherwise phosphorylates beta-catenin.
crinkled mutants fail to properly develop the flies auditory organs and they are deaf [30], [31].
ceh-36 null mutants fail to respond to any AWC-sensed odorants [21], [22], [23].
