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Consistent with this, WS cells expressing the mutants exhibited less DNA repair efficiency and more sensitivity to etoposide, compared to those expressing wild type.
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In contrast, foxo mutants exhibit less wasting.In people, many infections--including tuberculosis--can cause wasting, much as we see in Drosophila.
The shape of several elements was affected, with the mutants exhibiting less tapering of the distal humerus and less flaring of the proximal radius, but unchanged flaring of the proximal tibia.
The SOFL1-RNAi62 sofl2-1 exproducedroduced smaller callus than control explants at 25 and 50 ng ml−1 kinetin in this assay (Figure 5), suggesting that the double mutant exhibited less sensitivity to exogenous cytokinins.
More specifically, infection of piglets with a ciaB mutant exhibited less severe disease as compared to a C. jejuni wild-type strain, as judged by clinical presentation and histopathology [ 14].
We found that mice infected with the C. jejuni ciaD mutant exhibited less severe disease when compared to the C. jejuni wild-type strain, as judged by mouse survival (Additional file 9: Figure S9A), gross pathology, histopathology and plasma IgG2b anti- C. jejuni antibody levels (Additional file 10: Figure S10).
The thin cells of the im mutant fibers exhibited less efficient SCW biosynthesis.
Indeed, being almost redundant in single mutants, Rpf proteins exhibited less redundancy in double and triple mutants.
From our analysis, it is well revealed that native complex forms more number of NH bond with crizotinib with an average of ~3 NH bonds), while the mutant complex F1174L exhibited less number of intermolecular NH bonds of an average of ~1-2 and 4(c)).
Cross between the MATα CWC1 overexpression ssn8 mutant and MATa ssn8 mutant (Fig. 10l) exhibited less filamentation than the ssn8 bilateral mutant cross (Fig. 10d).
In contrast, the other three deletion mutants Plin2-I, Plin2-N1, and Plin2-N2 exhibited less α-helical structure than full-length Plin2 based on both methods of analysis with results showing a respective 16.4%, 10.5%, and 16.5% α-helical structure (regular and distorted).
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