Sentence examples for mutants equivalent to from inspiring English sources
What is distinctive in the theory is the claim that at each gene locus there are several favourable mutants, equivalent to one another with respect to adaptation, so that they are not subject to natural selection among themselves.
The #km parameter represents the number of killed mutants; the #tm defines the total number of generated mutants; and #em denotes the number of mutants equivalent to the original SUT.
Regardless, previous research also showed that the CMG2 S113L and V115G mutants (equivalent to positions 113 and 115 in TEM8) cause no change in protective ability [33].
Furthermore, mouse Tom1L1 mutants equivalent to human Tom1L1/Y460F (lane 6) or Tom1L1/Y392F (lane 7) also failed to rescue the defect of EGFR endocytosis in the knockdown cells.
Moreover, structural analysis of the KpBest L177T mutant (equivalent to hBest1 I201T) provides further insights into ATP binding and channel activation.
On the other hand, R172H p53 mutant, equivalent to human R175H, is a structure defective mutant whose point mutation determines an important conformational alteration [46].
Our molecular modeling shows that mouse D606G mutant, equivalent to the human D658G mutation, is located in the seventh β-propeller of the second domain.
A recent report showed that the fly SAS6 mutant equivalent to human SAS-6F131E could support the formation of some centriole-like structures in vivo (Cottee et al., 2015).
However, the W280E mutant (equivalent to TEAS W273E) of the orthologous TEAS-like TPS, premnaspirodiene synthase from Hyoscyamus muticus (HPS), yields an alkylated tryptic peptide I[522 528]K consistent with the alkylation of the tyrosine corresponding to TEAS-Tyr520.
The authors then validate their structure through multiple approaches, including the rescue of mutants in the C-lobe through mutation of opposing residues in the N-lobe, and using a point mutant equivalent to a key mutation in Angelman's Syndrome, they underscore the medical relevance of their studies.
The structure of the KAR3 E631A mutant (equivalent to E236A) confirms that the mutated side chain can no longer interact strongly with the P-loop (Yun et al., 2001), supplying an explanation for the increased ADP off rate in the detached state of this mutant.
