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The morphants and mutants displayed partial rescue by l-Leu treatment (Fig. 5).
The Shh CreERT2/+ ; β-catenin flox ex3)/+ ; BmprIA flox/− mutants displayed partial restoration of URS elongation compared with the β-catenin GOF mutants.
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From this primary screen, we identified ten mutants that displayed partial rescue following p53 morpholino injection (hi821a, hi1045, hi1477, hi2404, hi2877b, hi2865, hi2975, hi3635, hi3662, hi3820a).
Type 2B VHL mutant R167Q cells displayed partial suppression of HIF-2α while retaining HIF-2α stabilization in response to CoCl2.
In contrast, ser-1 (ok345 ) mutants displayed a partial serotonin-resistant phenotype.
However, RNAi knockdown of either Roc2 or Cul5 mRNA in a cul-2 mutant background caused complete sterility, whereas cul-2 mutants only display partial sterility.
In breeding experiments, maternal-zygotic Mbtps1 wrt mutant offspring (homozygotes derived from homozygous mutant mothers) displayed fully penetrant embryonic lethality, whereas zygotic mutant offspring (homozygotes derived from heterozygous mothers) displayed partial (~40%) embryonic lethality, and heterozygous mutant offspring of homozygous mothers were fully viable.
In contrast, C39 displayed partial α-cleavage inhibition in both Hpl and HeLa cells, which is in agreement with the finding that a mutant bearing a deletion of the region 114 121 is inefficiently cleaved in the brain of transgenic mice [14].
Honokiol hereby displayed partial PPARγ agonism.
ADPM01 displayed partial co-localisation with mitochondrial regions.
Wild-type P2X2 displayed partial resistance to EndoH treatment.
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