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Best Canadian Short Film: "Mutants," directed by Alexandre Dostie.
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However, such mutant screens are not directed by natural variation in phenotype and there is no reason to expect that genes identified through induced mutation (or other means of disrupting gene function) are those that have been acted upon by natural selection, which could render them interesting but unimportant in an ecological/evolutionary context.
To compare intracellular protein synthesis directed by the mutant FMDVs, proteins were metabolically labeled between 3 and 4 hours post electroporation. BHK 21 cells infected with mutants V3, V19 4 and V15 9 encoding R55W in 2C presented modestly higher levels of viral proteins than the same mutants expressing a wild type 2C (Figure 7).
Since recombination frequency of sex chromosomes is comparatively low in male meiosis (Tripathi et al. 2009a), this experimental design minimized the amount of pattern variation caused by X chromosomes derived from different strains, thereby allowing us to study the influence of the mutant autosomal genes on the pattern directed by a given Y chromosome.
She plays Rogue, a genetic mutant, in the big-budget adaptation of superhero comic book X-Men, directed by Bryan Singer (The Usual Suspects).
Directed by Susanne Bier.
Directed by Alejandro Chomski.
Directed by Shonali Bose.
Directed by Andrey Boreyko.
Directed by Orson Welles.
Directed by Zach Helm.
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