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Even though we detected a change in muscle physiology, where the decay times of mEPCs in the mutants differed from siblings, this difference did not compare with the differences in decay times documented for twister mutants and stage-matched twister siblings (see Lefebvre et al., 2004; Figure 6).
These results indicate that the endosperm starch components in both sugary mutants differed from those in the wild type, and starch production was at least partially restored in the sug-h endosperm.
CPS profiles of all untreated mutants differed from that of the wt protein.
Despite targeting the same or adjacent residues of the protein, these mutants differed from each other in the levels of resistance they provided.
To investigate whether the subcellular localization of mutants differed from that of their wild-type (WT) counterparts, we transiently expressed N-terminal green fluorescent protein (GFP -tagged FABPs in Neuro2A cells (a murine neuroblastoma cell-line).
Accordingly, mop1-1 homozygous plants were assayed for local nucleosome occupancy at transcription start sites (TSSs) of approximately 400 genes in maize, resulting in the identification of small number of distinct examples where nucleosome occupancy in mutants differed from WT.
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As such these two mutants differ from the D136A mutant, a constitutive V2 receptor identified only in heterologous expression systems and which exhibit strong constitutive and regulated activities [12].
In search of a biochemical explanation for the unanticipated results described above, we determined whether the cancer-derived TRKB mutants differ from wild-type TRKB in their responsiveness to BDNF.
Missense mutants differ from the WT protein by only a single residue.
However, how these mutants differ from the wild type is not fully understood.
Single mutants differing from WT as well as all double mutants were profiled another two times from an independently inoculated culture.
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