Sentence examples for mutants demonstrated that from inspiring English sources

Finally, infection of Drosophila melanogaster with null mutants demonstrated that KerV orthologs are also crucial in Vibrio cholerae and Yersinia pseudotuberculosis pathogenesis.

Studies using oshkt2 1 null mutants demonstrated that OsHKT2 1 (or OsHKT1) takes up Na+ under K+-starvation conditions [57].

Examination of a panel of individual or clustered lysine mutants demonstrated that lysine 613 (K613) in the cytoplasmic tail of Dll1 is a key residue necessary for transcellular activation of Notch signaling.

The studies of HvCPI, a group I phytocystatin from barley, and a series of its site-directed mutants demonstrated that antifungal activity of HvCPI is not related to its inhibitory property against cysteine protease (Martinez et al. 2003).

In Drosophila, studies with cohesin mutants demonstrated that cohesin is required for developmental axonal pruning [28] and abnormal cohesin complex cleavage alters wild type larval locomotion [29].

The generation of CD9P-1 mutants demonstrated that the transmembrane and the cytoplasmic domains are necessary for inducing effects on cell motility.

However, SMX had no effect on nuc-1 mutants, demonstrating that animals maintain a functional folate cycle.

Taken together, the results with the chimeras and stop mutants demonstrate that the C2HC ZnF of RNF125 is essential for ubiquitin ligase activity, and that residues 120 128 of linker 2 (Li2120-128) further enhance activity.

Mutational analysis of Py-I (nucleotides 120 to 130), supported by compensatory mutants, demonstrates that the primary sequence of this motif is not important but that a helical structural element associated with this region is critical for HCV IRES function.

In vivo analysis of smy1Δ mutants demonstrates that this "damper" mechanism is critical for maintaining proper actin cable architecture, dynamics, and function.

Moreover, the occurrence of duplication of the targeted chromosome was strikingly increased in the exo1Δ sgs1Δ double mutant but not in the respective single mutants demonstrating that the Exo1 and Sgs1 proteins independently suppress whole chromosome duplication during gene targeting.