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We also show that both insertion mutants demonstrate enhanced tumorigenicity in nude mice.
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102 104 Both tomato and Arabidopsis abscisic acid- deficient mutants demonstrated enhanced resistance to necrotrophs, which is attributed to induced transcription of JA/ET-responsive genes and timely production of hydrogen peroxide.
The ΔgcvT mutant demonstrated enhanced 13C flux into the glycine pool under chase conditions.
Using the glycolate-accumulating ΔglcD1 mutant, we demonstrate enhanced 13C partitioning into the glycolate pool under conditions favouring photorespiration and enhanced 13C partitioning into the glycine pool of the glycine-accumulating ΔgcvT mutant.
Thus, for the majority of THO complex mutants, the diploid deletions demonstrate enhanced DOX sensitivity when compared to the isogenic haploid derivatives.
However, ap2c3 and ap2c3/ap2c1 mutant plants have been recently reported to demonstrate enhanced ABA-insensitive phenotypes during germination and increased stomata aperture along with enhanced ABA-induced MAPK-activities [31].
In contrast, transgenic mice expressing a dominant negative IκBα mutant protein under the control of epithelial specific promoters demonstrate enhanced collagen deposition and apoptosis in their lungs in response to silica.
In contrast, transgenic mice expressing a dominant negative IκBα mutant protein under the control of epithelial cell specific promoters demonstrate enhanced apoptosis and collagen deposition in their lungs in response to silica.
Mutant sCPCAcyLeu666Phe and sCPCAcyLeu677Ala exhibited significantly reduced specific enzymatic activity, while mutant sCPCAcyAla675Gly demonstrated enhanced activity.
Conversely, the ethylene-resistant mutant ein2-1 denhancedted enhanced sensitivity to ABA in seed germination assays, consistent with previous reports that reduced ethylene sensitivity results in increased ABA sensitivity in seed germination assays (Beaudoin et al. 2000; Ghassemian et al. 2000).
Of 30 mutants tested, 24 demonstrated enhanced sensitivity to doxorubicin as both a diploid and an isogenic haploid when compared to the repair competent WT strains.
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