Sentence examples for mutants could lead from inspiring English sources

This finding offers clues regarding the allosteric mechanism and suggests that future analysis of the effects of single site HscB mutants could lead to a better understanding of the contributions of individual interface residues to the enzymatic activity of the ternary complex.

The presence of high endogenous level of ABA in the seeds of rad mutant could lead to ABA dependent signaling via serine/threonine kinases.

Rapid changes in mtDNA heteroplasmy have been observed within a single generation, and so any 'leakage' of mutant mtDNA could lead to mtDNA disease in future generations, compromising the reproductive health of the first generation, and leading to repeated interventions in subsequent generations.

Alternatively, intracellular sequestration of mutant heterotrimers could lead to extracellular deficiency of α1α1α2 heterotrimers.

Because CaM regulates many other Ca2+ channel subtypes, including those that predominate in neurons, these mutant CaMs could lead to a multi-system disorder similar to TS.

Although the ldh and pfl double mutant strain could lead to an improved succinate production to about 28.2 g/L, this strain lost its ability to ferment glucose anaerobically due to redox imbalance [ 33].

Either deficiency of normal heterotrimers or presence of mutant heterotrimers could lead to compromised basement membranes that perturb cell matrix signaling via cell surface receptors or growth factor-mediated cell cell signaling.

Indeed, reduced striatal TrkB expression has been reported in knockin HD cellular and mouse models, exon-1 HD transgenic mice and HD human brain, which suggests that mutant huntingtin could lead to reduced neurotrophic support not only by altering BDNF levels but also by affecting TrkB expression.