Sentence examples for mutants could cause from inspiring English sources

In such a scenario, the INCENP mutants could cause premature spindle localization of the CPC, leading to activation of Aurora B on the spindle instead of at the centromere [ 40].

Next, we tested whether expression of STBD1 mutant proteins could cause relocalization of GDE.

Not only mutant KCTD could cause diseases, but also the change of KCTD expression involved in different diseases [ 22, 43- 46].

Reduced aminoacylation activity of the mutant enzyme could cause decreased mitochondrial protein synthesis and consequent mitochondrial respiratory chain dysfunction.

Our data support the clinical descriptions of distal HMN type II implying that mutant HSPB8 could cause defects in preserving specifically motor neuron axons.

A ΔtpiA mutant alone could cause methylglyoxal accumulation and inhibit the anaerobic growth [ 34], but re-directing flux to the ED pathway should prevent methylglyoxal accumulation.

Based on the above results one might speculate that the increased pericyte coverage of the tumor vasculature observed in D849N-mutant mice could cause accelerated establishment of tumors due to improved vessel function.

The marginal levels of telomerase in the cell, Hockemeyer said, result is some unprotected chromosome ends in the surviving mutant cells, which could cause mutations and further fuel tumor formation.

Despite overexpression of the mutant protein which could cause excessive secretion, the extent of its intracellular retention was 5.5 ± 1.3%, which was even higher than for wild-type dCREG-V5His (1.1 ± 0.1%; p = 0.029).

Moreover, the reassortant viruses with mutant H5 HA could cause droplet transmission in ferrets, suggesting that H5N1 virus with pandemic potential may emerge with continuous viral circulation and evolution.

They state that masking the mutated region of the CFTR polypeptide with a corresponding WT fragment could cause the mutant to escape the ER [ 32, 33].