Sentence examples for mutants could affect from inspiring English sources

To illustrate the functional importance of the binding between PHD1KDM5B and the unmodified H3K4, we tested whether the mutants could affect the expression of tumor suppressor genes compared with wild-type KDM5B.

Next, we examined if these EBV-Z mutants could affect the functions of K-RTA.

Thus, it was important to evaluate whether the interface mutants could affect the rate of GTP hydrolysis on the ribosome.

Moreover, considering that HSPBs are known to form oligomers with other members of the same family, it is possible that HSPB mutants could affect the function of other HSPBs via dominant-negative effects.

It remains to be investigated if the null phosphatase mutants could affect other aspects of the A. fumigatus biology, such as sexual cycle or other stages of the life cycle.

We hypothesized that the identity defects and disorganization of root outer cell layers in docs1 mutant roots could affect root gravitropism.

This implies that a relay of interactions links D211 and PPi and that alteration of that relay by N211 in the mutant enzyme could affect the apparent affinity of PPi for the enzyme.

Taking into account these observations, it is conceivable to hypothesize that mutant p53 could affect many aspects of cancer stem cell formation and expansion.

Reportedly, PTEN protein not only functions autonomously within cells, but is secreted and taken up by surrounding cells; this raises the possibility that mutant proteins could affect the microenvironment in a dominant-negative fashion.

We predicted that this would lead to a failure of splicing of the intron in the mutant that could affect the initiation of translation leading to lower levels of expression of eRF1.

The different electrostatic potential distribution for the CaM binding region in the Fas DD was observed between the Fas DD and the Fas DD V254N mutant, which could affect the electrostatic interactions between the Fas DD and CaM.