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vps22 and vps25 mutants contain increased Notch activity and heterozygosity of Notch suppresses the non-autonomous overgrowth phenotype.
Combined, these data suggest that D-cbl mutants contain increased EGFR activity suggesting that D-cbl negatively controls EGFR activity.
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In Figure 2, we showed that vps22 and vps36 mutant clones contain increased Notch protein levels.
D-cbl mutant ommatidia contain increased numbers of R7, cone and pigment cells.
Mutant ommatidia contain increased numbers of photoreceptors (mostly R7), cone and pigment cells.
Thus, although vps22, vps25 and vps36 mutants display similar endosomal defects and contain increased Notch protein levels, they affect mosaic animals differently.
These same transcripts are associated with TDP-1 and contain increased amounts of dsRNA structure/abundance in tdp-1 mutants.
Thus, it is likely that chromatin of CAF-1 mutant trichomes contains increased amounts of the H3.2 variant histone.
Finally, staphylococcal thermonuclease was shown to be involved in biofilm development as a nuc mutant formed a thicker biofilm containing increased levels of matrix-associated eDNA.
In the current study, biofilms produced by the nuc mutant UAMS-14711) were thicker and contained increased levels of eDNA in the matrix compared to the parental and complemented strains (Fig. 6).
Sweat contains increased amounts of oil.
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