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By comparison, about 50% of p53 zdf1/zdf1 mutants with abdomen and eye tumors exhibited thin (n=5/16, Fig. 5A,B) or dilated blood vessels (n=3/16), but the degree of dilation was not as marked when compared with abnormal dilated blood vessels in tsc2 p53 mutants (comparison to tsc2 p53 mutants not statistically significant with P=0.33 by two-tailed Fisher's exact test).
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Variance is substantially lower for the one-step mutants in comparison to all mutants, again suggesting that the wild-type sequence is fairly robust to nearby changes in sequence space.
There were no notable differences in growth in fertilized soil of the sultr1 3 and sultr2;1 mutants in comparison to phr1 mutant or WT plants (data not shown).
In this respect it is important to note that, while protease production remained elevated in sarA/agr mutants by comparison to the parent strains, it was reduced by comparison to the corresponding sarA mutants (Fig. 6).
When assaying the cisplatin sensitivity of 47 deletion mutants belonging to the proteasome pathway, we identified a number of cisplatin sensitive and resistant mutants in comparison to the corresponding wild-type strains (Table 2).
In contrast, we found no consistent statistically significant differences between the fatty acid profile of either leaves or roots of SACPD-C mutants in comparison to parental lines (although we observed slight differences between Williams 82 and the EMS induced mutant line 194d).
Thus, water transport is impaired in esk1 mutants in comparison to wild type and probably induces the low evapo-transpiration and the reduced RWC observed in the mutants.
Because we identified AR mutants with defects in components of auxin, ethylene, and ABA response, we examined several known auxin, ethylene, and ABA mutants for comparison to our unknown isolates.
We assessed lipid stores in all of the three mutants in comparison to wild type.
An enhanced O-GlcNAc modification of OGT was observed in cells transfected with PHB mutants in comparison to wild type PHB in response to insulin only (Fig. 3B).
There were no significant changes observed in the mutants in comparison to PstPc, thus reinforcing the importance of Arg20, Asp38 and Asp229 residues.
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