Sentence examples for mutants causing the from inspiring English sources

Proinsulin mutants causing the MIDY syndrome are distinct both from insulinopathies previously described as associated with adult onset-associated diabetes [3] and from recessive alleles that result in neonatal diabetes through reduced insulin expression [18].

Based on our mechanical fractionation study and secretion assay it is tempting to speculate that the interactions between EvpC and EvpI might be disrupted in these mutants causing the abolition of secretion.

This estimate assumes uninterrupted exponential growth, but nevertheless it is well under the 53 h of the first experiment, meaning that even in adding an initial lag phase and final competition (i.e. stationary phase) to the growth estimate, it would be consistent with a small number of initial mutants causing the rescue.

These observations suggest that the reduced levels of Pio accumulation in the tracheal lumen in γCOP mutants cause the disruption of dorsal branches.

Thus, miRNA mutants cause the inflorescence transcriptome to resemble leaf and meristem transcriptomes and to diverge from pollen and seed transcriptomes.

Since Baz is essential for proper targeting of Crb and AJ [6], [7], mispositioned Baz in cnn mutants causes the defects of Crb and AJ (Figure 4B).

Overexpression of α-Syn, through its gene duplication and triplication, is linked to idiopathic Parkinson's disease (PD), while its A30P and A53T mutants cause the autosomal dominant forms of familial PD [2] [4].

Similarly to the wild type variant of vimentin these mutants caused the decreased mitochondrial motility (Fig. 5).

Several mutants caused the formation of chromatin bridges between mitotic nuclei (Fig. 5B), as seen when embryos develop without detectable Xpd (Li et al., 2010).

The results are consistent with an autosomal dominant mutant causing the white phenotype.

It appears that Na+ ions can substitute for protons and bind to the counterion in the initial state of the D251E mutant, causing the red shift of the absorption spectrum.