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Thus, reduced accumulation of Pio in the tracheal lumen in γCOP mutants causes a pio-like defect in dorsal branch formation.
We conclude that none of the mutants causes a substantial decrease in Dna2-GFP expression or in nuclear abundance of Dna2-GFP.
One possibility is that uterine tumors can contribute to mortality and that increased tumor formation in mdl-1 0) mdl-1 0 causes a shortened lifespan.
In fact, the presence of 12 transgenic His-GUs in the genome of the His C mutants causes a reversion of the mutant M15 pattern to that of wild-type embryos (Fig 2C; supplementary Fig S7 online).
However, only triple mutants (er105, erl1-2, erl2-1) fail to form one or more of the four anther lobes; none of the single mutants causes a severe anther phenotype.
The timely and spatially stochastic alteration of cell division and PIN1 polarity in the embryo epidermis of rpk1 mutants causes a variable development of the cotyledon primordia, in particular the complete loss of one cotyledon indicating an early developmental accident during globular embryo stages [ 22].
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Reducing cellulose content by the procuste1 or fei1 fei2 mutants causes an increase in lignin content [ 16, 33].
Furthermore, overexpression of CMT2B-causing Rab7a mutants caused a strong increase of soluble vimentin (Fig. 4E F).
Reintroduction of a functional RRN5 gene into Sup mutants caused a reduction in the number of rDNA repeats to close to the wild type level but did not change RNA content.
We therefore tested whether the shs1-ps mutants cause a phenotype that is similar to shs1Δ.
APC mutants cause a strong activation of canonical Wnt signaling that leads to arrest prior to gastrulation [36].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com